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Found 2 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 20' and Ligand = 'BDBM50556597'
TargetMitogen-activated protein kinase kinase kinase 20(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50556597(CHEMBL4756586)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of C-terminal NanoLuc-fused full length ZAK (unknown origin) expressed in HEK293T cells after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 20(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50556597(CHEMBL4756586)
Affinity DataKd:  120nMAssay Description:Inhibition of wild-type human partial length ZAK (M1 to L331 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed