Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase kinase 1' and Ligand = 'BDBM519645'
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM519645(US11142525, Example 46 | US11684616, Example 300)
Affinity DataKi:  0.140nMAssay Description:PRKD2 (PKD2) and RPS6KA2 (RSK3) kinase assays were performed with Km-levels of ATP at the Thermo Fisher Scientific, Inc. (Madison, Wis.), using their...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM519645(US11142525, Example 46 | US11684616, Example 300)
Affinity DataKi:  0.140nMAssay Description:HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay (MSA). The reactions were conducted in 50 μL volumes in 96-well pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent