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Found 4 Enz. Inhib. hit(s) with Target = 'Monoacylglycerol lipase ABHD6' and Ligand = 'BDBM50211257'
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211257(CHEMBL3895863 | US10583137, Compound 14)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211257(CHEMBL3895863 | US10583137, Compound 14)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of human recombinant ABHD6More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211257(CHEMBL3895863 | US10583137, Compound 14)
Affinity DataIC50:  79nMAssay Description:Inhibition of MB064 probe binding to ABHD6 in mouse brain membrane proteome preincubated for 30 mins followed by MB064 probe addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211257(CHEMBL3895863 | US10583137, Compound 14)
Affinity DataIC50:  126nMAssay Description:Inhibition of ABHD6 in mouse brain membrane using HT-01 probe as substrate incubated for 30 mins by gel based competitive ABPP assayMore data for this Ligand-Target Pair
In DepthDetails PubMed