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Found 2 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50305369'
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305369((1S,3aR,6aR)-2-methyl-5-(6-phenylpyridazin-3-yl)-1...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]585539 from alpha7 nAChR in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305369((1S,3aR,6aR)-2-methyl-5-(6-phenylpyridazin-3-yl)-1...)
Affinity DataEC50:  1.29E+4nMAssay Description:Agonist activity at human recombinant alpha7 nAChR expressed in xenopus oocytes assessed as induction of Ca2+ currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed