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Found 6 Enz. Inhib. hit(s) with Target = 'Nicotinamide N-methyltransferase' and Ligand = 'BDBM50455095'
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Harvard University

Curated by ChEMBL
LigandPNGBDBM50455095(CHEMBL4206972)
Affinity DataIC50:  1.39E+3nMAssay Description:Inhibition of human NNMT measured after 20 mins by luminescence based methyltransferase assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Harvard University

Curated by ChEMBL
LigandPNGBDBM50455095(CHEMBL4206972)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibitory activity against cell free dihydrofolate reductase (DHFR) from Candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Harvard University

Curated by ChEMBL
LigandPNGBDBM50455095(CHEMBL4206972)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibitory activity against cell free dihydrofolate redutase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Harvard University

Curated by ChEMBL
LigandPNGBDBM50455095(CHEMBL4206972)
Affinity DataIC50:  2.37E+3nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Mus musculus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50455095(CHEMBL4206972)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory activity against cell free dihydrofolate redutase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Mus musculus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50455095(CHEMBL4206972)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibitory activity against cell free dihydrofolate redutase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed