BindingDB PrimarySearch_ki

Found 1 Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TYK2/Tyrosine-protein kinase JAK1/Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50021656'

Non-receptor tyrosine-protein kinase TYK2/Tyrosine-protein kinase JAK1/Tyrosine-protein kinase JAK2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50021656(BARICITINIB | INCB-028050 | LY-3009104 | US1011290...)

IC50: 21nMAssay Description:Inhibition of JAK1/JAK2/TYK2 in human whole blood assessed as inhibition of IL-6-induced STAT-1 phosphorylation preincubated for 45 mins followed by ...More data for this Ligand-Target Pair

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3D Structure (crystal)