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Found 2 Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM50438810'
TargetOrexin receptor type 2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50438810(CHEMBL2413511 | US8680275, 118)
Affinity DataKi:  40nM ΔG°:  -39.3kJ/moleT: 2°CAssay Description:HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM 001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50438810(CHEMBL2413511 | US8680275, 118)
Affinity DataKi:  40nMAssay Description:Antagonist activity at human orexin receptor 2 expressed in CHO cells assessed as inhibition of orexin-A-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed