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Found 2 Enz. Inhib. hit(s) with Target = 'Orotidine-5'-phosphate decarboxylase' and Ligand = 'BDBM21335'
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
Toronto General Research Institute

LigandPNGBDBM21335(6-cyanouridine 5-monophosphate | C6-Uridine Deriva...)
Affinity DataKi:  2.60E+4nM ΔG°:  -27.2kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium vivax (malaria parasite P. vivax))
Toronto General Research Institute

LigandPNGBDBM21335(6-cyanouridine 5-monophosphate | C6-Uridine Deriva...)
Affinity DataKi:  6.20E+4nMpH: 7.5Assay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed