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Found 1 Enz. Inhib. hit(s) with Target = 'Presenilin-1' and Ligand = 'BDBM50522627'
TargetPresenilin-1(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50522627(CHEMBL4590743)
Affinity DataIC50:  107nMAssay Description:Inhibition of gamma secretase in human SKNBE2 cells expressing human APP695 assessed as increase in Abeta38 levels incubated for 18 hrs by sandwich E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed