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Found 5 Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM50085415'
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50085415(3-(3,5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1,3-d...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of cRAF1 (unknown origin) at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50085415(3-(3,5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1,3-d...)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of human CRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50085415(3-(3,5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1,3-d...)
Affinity DataIC50:  9nMAssay Description:Inhibition of cRAF1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50085415(3-(3,5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1,3-d...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Raf-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50085415(3-(3,5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1,3-d...)
Affinity DataIC50:  10.6nMAssay Description:Inhibition of human RAF1 using MEK1 as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed