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Found 6 Enz. Inhib. hit(s) with Target = 'Reverse transcriptase' and Ligand = 'BDBM50033885'
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50033885(CHEMBL3263468)
Affinity DataIC50:  40nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50033885(CHEMBL3263468)
Affinity DataIC50:  40nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50033885(CHEMBL3263468)
Affinity DataIC50:  50nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase V106A mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50033885(CHEMBL3263468)
Affinity DataIC50:  70nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase L100I mutant assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50033885(CHEMBL3263468)
Affinity DataIC50:  540nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase K103N mutant assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50033885(CHEMBL3263468)
Affinity DataIC50:  8.23E+3nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase Y181I mutant assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed