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Found 4 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Chk1' and Ligand = 'BDBM50524300'
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Sumitomo Pharma

US Patent
LigandPNGBDBM50524300(LY2606368 | Prexasertib | US11564920, Example Prex...)
Affinity DataIC50:  0.540nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHK1tide (R7185, Molecul...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Sumitomo Pharma

US Patent
LigandPNGBDBM50524300(LY2606368 | Prexasertib | US11564920, Example Prex...)
Affinity DataIC50:  0.560nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged CHK1 (M1 to T476 residues) expressed in baculovirus infected insect cells using biotin-labelled...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Sumitomo Pharma

US Patent
LigandPNGBDBM50524300(LY2606368 | Prexasertib | US11564920, Example Prex...)
Affinity DataIC50: <1nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Sumitomo Pharma

US Patent
LigandPNGBDBM50524300(LY2606368 | Prexasertib | US11564920, Example Prex...)
Affinity DataIC50: <1nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed