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Found 2 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM238805'
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM238805(US9394297, 492)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM238805(US9394297, 492)
Affinity DataIC50:  0.100nMpH: 7.0 T: 2°CAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent