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Found
1
Enz. Inhib. hit(s) with Target = 'Tryptophan 5-hydroxylase 1' and Ligand = 'BDBM341714'
Target
Tryptophan 5-hydroxylase 1
(Homo sapiens (Human))
Actelion Pharmaceuticals
US Patent
Ligand
BDBM341714
(1-(5-(4-Chloro-2-fluorophenyl)-2-methyl-7,8-dihydr...)
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Affinity Data
IC50: 3nM
Assay Description:
To generate the enzyme, full length human TPH1 is cloned into the plasmid pET20b(+) (Novagen) and expressed in E. coli. The bacterial cells are ruptu...
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Ligand Info
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