Found 3 Enz. Inhib. hit(s) with Target = 'Tumor necrosis factor ligand superfamily member 11' and Ligand = 'BDBM50373071' TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 1.38E+4nMAssay Description:Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 1.38E+4nMAssay Description:Binding affinity to human RANKL measured after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
