Found 8 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM50459553' 
Affinity DataIC50: 0.390nMAssay Description:Inhibition of N-terminal DYKDDDDK tagged biotinylated unactivated human recombinant BTK using FITC-labeled Srctide peptide substrate by by mobility s...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of N-terminal DYKDDDDK tagged biotinylated activated human recombinant BTK using FITC-labeled Srctide peptide substrate by mobility shift ...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of BTK in human PBMC assessed as reduction in anti-IgM-stimulated B-cell activation by measuring CD86 expressionMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of anti-IgM-stimulated BTK phosphorylation at Tyr223 in human Ramos cells pre-incubated for 1 hr followed by anti-IgM stimulation for 10 m...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of anti-IgM-stimulated BTK phosphorylation at Tyr551 in human Ramos cells pre-incubated for 1 hr followed by anti-IgM stimulation for 10 m...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of anti-IgM-stimulated BTK-mediated PLCgamma2 phosphorylation at Tyr1217 in human Ramos cells pre-incubated for 1 hr followed by anti-IgM ...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of BTK phosphorylation in human whole blood assessed as reduction in BTK phosphorylation incubated for 30 minsMore data for this Ligand-Target Pair
