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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2 [808-1132]' and Ligand = 'BDBM349119'
Target
Tyrosine-protein kinase JAK2 [808-1132]
(Homo sapiens (Human))
Galapagos
US Patent
Ligand
BDBM349119
(Cyclopropanecarboxylic acid [5-(4-phenoxymethyl-ph...)
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Affinity Data
IC50: <100nM
Assay Description:
Recombinant human JAK2 catalytic domain (amino acids 808-1132; catalog number PV4210) was purchased from Invitrogen. 0.025 mU of JAK2 was incubated w...
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Target Info
PDB
UniProtKB/SwissProt
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Ligand Info
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In Depth
Details
US Patent
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