Compile Data Set for Download or QSAR
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Report error Found 5 Enz. Inhib. hit(s) with all data for assayid = 4 entry = 50012606
TargetKappa-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataIC50:  140nMAssay Description:Antagonist activity at human KOR expressed in CHO cell membranes assessed as reduction in U50,488 induced response incubated for 1 hr by liquid scint...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetKappa-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50558720(CHEMBL4754076)
Affinity DataIC50:  220nMAssay Description:Antagonist activity at human KOR expressed in CHO cell membranes assessed as reduction in U50,488 induced response incubated for 1 hr by liquid scint...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50558710(CHEMBL4745486)
Affinity DataIC50:  750nMAssay Description:Antagonist activity at human KOR expressed in CHO cell membranes assessed as reduction in U50,488 induced response incubated for 1 hr by liquid scint...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50558717(CHEMBL4762413)
Affinity DataIC50: >2.50E+3nMAssay Description:Antagonist activity at human KOR expressed in CHO cell membranes assessed as reduction in U50,488 induced response incubated for 1 hr by liquid scint...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50558708(CHEMBL4797769)
Affinity DataIC50: >2.50E+3nMAssay Description:Antagonist activity at human KOR expressed in CHO cell membranes assessed as reduction in U50,488 induced response incubated for 1 hr by liquid scint...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed