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Found 4 of ec50 for monomerid = 50017228
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50017228(CHEMBL3287676 | US10099993, Compound 25)
Affinity DataEC50:  451nMAssay Description:Positive allosteric modulation of rat mGluR2 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced thallium flux incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50017228(CHEMBL3287676 | US10099993, Compound 25)
Affinity DataEC50:  451nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017228(CHEMBL3287676 | US10099993, Compound 25)
Affinity DataEC50:  3.40E+3nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50017228(CHEMBL3287676 | US10099993, Compound 25)
Affinity DataEC50:  3.40E+3nMAssay Description:Positive allosteric modulation of rat mGluR3 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced thallium flux incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed