Found 5 of ic50 for monomerid = 208679 TargetC-X-C chemokine receptor type 3/Guanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
Actelion Pharmaceuticals
US Patent
Actelion Pharmaceuticals
US Patent
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at recombinant human CXCR3 expressed in human CHO-K1 cells co-expressing Galpha15 incubated for 10 mins by Fluo-4AM dye based FLI...More data for this Ligand-Target Pair
Affinity DataIC50: 561nMAssay Description:Inhibition of CXCR3 receptor internalization in human venous whole blood incubated for 30 mins by flow cytometer analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 862nMAssay Description:Antagonist activity at recombinant human CXCR3 in human U2SO cells assessed as reduction in CXCL10-induced beta-arrestin recruitment by TANGO assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 960nMAssay Description:Inhibition of hERG expressed in CHO cells by Q patch-clamp methodMore data for this Ligand-Target Pair
