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Found 2 of ic50 for monomerid = 278480
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM278480((2R)-2-(dimethylamino)-N-[5-[[(3R)-1-pyridazin-3-y...)
Affinity DataIC50:  2.26E+3nMpH: 7.8 T: 2°CAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM278480((2R)-2-(dimethylamino)-N-[5-[[(3R)-1-pyridazin-3-y...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human KGA (63 to 669 residues) preincubated for 15 mins using 50 mM glutamine as substrate by resorufin dye based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed