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Found 2 of ic50 for monomerid = 380973
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM380973(6-(4-Hydroxy-4-methyl-3,4-dihydro- 1H-pyrano[4,3-c...)
Affinity DataIC50:  15nMAssay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM380973(6-(4-Hydroxy-4-methyl-3,4-dihydro- 1H-pyrano[4,3-c...)
Affinity DataIC50:  42.8nMAssay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent