Compile Data Set for Download or QSAR
maximum 50k data
Found 4 of ic50 for monomerid = 384215
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
The University of Texas System

US Patent
LigandPNGBDBM384215((4S)-8-[3-(2-amino- 5-chloropyridin-4- yl)-1H-pyra...)
Affinity DataIC50:  504nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
The University of Texas System

US Patent
LigandPNGBDBM384215((4S)-8-[3-(2-amino- 5-chloropyridin-4- yl)-1H-pyra...)
Affinity DataIC50:  504nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
The University of Texas System

US Patent
LigandPNGBDBM384215((4S)-8-[3-(2-amino- 5-chloropyridin-4- yl)-1H-pyra...)
Affinity DataIC50:  504nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
The University of Texas System

US Patent
LigandPNGBDBM384215((4S)-8-[3-(2-amino- 5-chloropyridin-4- yl)-1H-pyra...)
Affinity DataIC50:  1.03E+3nMAssay Description:KYSE-520 cells (10 k cells/well) were grown in 384-well plate in 20 uL of medium (RPMI-1640, without phenol red, containing 10% FBS) at 37° C. with 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent