Compile Data Set for Download or QSAR
maximum 50k data
Found 4 of ic50 for monomerid = 398219
TargetInterleukin-1 beta(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398219(4-chloro-N-((3,3-difluoro-5-methylcyclohexyl)methy...)
Affinity DataIC50: <10nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 beta(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398219(4-chloro-N-((3,3-difluoro-5-methylcyclohexyl)methy...)
Affinity DataIC50: <10nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398219(4-chloro-N-((3,3-difluoro-5-methylcyclohexyl)methy...)
Affinity DataIC50:  55nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398219(4-chloro-N-((3,3-difluoro-5-methylcyclohexyl)methy...)
Affinity DataIC50:  55nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent