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Found 2 of ic50 for monomerid = 441812
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM441812(US10647665, Example I-1)
Affinity DataIC50:  46nMAssay Description:Inverse agonist activity at human RORgammat assessed as inhibition of N-terminal biotinylated co-activator SRC1 recruitment measured after 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM441812(US10647665, Example I-1)
Affinity DataIC50: <500nMAssay Description:1. Preparation of RORgamma Buffer Solution10 mL of DTT and 100 mL buffer solution were gently mixed together and ready to use.2. Preparation of Compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent