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Found 3 of ic50 for monomerid = 50069959
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
East China University of Science and Technology

US Patent
LigandPNGBDBM50069959(Brequinar sodium | CHEMBL300058 | Sodium; 6-fluoro...)
Affinity DataIC50:  8.45nMAssay Description:Principles of activity test at enzyme level: firstly, dihydroorotate (DHO) is oxidatively dehydrogenated by DHODH to form orotic acid (Orotate, OA), ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
East China University of Science and Technology

US Patent
LigandPNGBDBM50069959(Brequinar sodium | CHEMBL300058 | Sodium; 6-fluoro...)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant human DHODH activity after 20 mins by DCIP dye based colorimetric analysis in presence of 1 mM L-dihydroorotate and 1 mM Cq...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
East China University of Science and Technology

US Patent
LigandPNGBDBM50069959(Brequinar sodium | CHEMBL300058 | Sodium; 6-fluoro...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human recombinant N-terminal His-tagged DHODH (31 to 395 residues) expressed in Escherichia coli using DHO as substrate measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed