TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
East China University of Science and Technology
US Patent
East China University of Science and Technology
US Patent
Affinity DataIC50: 8.45nMAssay Description:Principles of activity test at enzyme level: firstly, dihydroorotate (DHO) is oxidatively dehydrogenated by DHODH to form orotic acid (Orotate, OA), ...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
East China University of Science and Technology
US Patent
East China University of Science and Technology
US Patent
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human DHODH activity after 20 mins by DCIP dye based colorimetric analysis in presence of 1 mM L-dihydroorotate and 1 mM Cq...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
East China University of Science and Technology
US Patent
East China University of Science and Technology
US Patent
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant N-terminal His-tagged DHODH (31 to 395 residues) expressed in Escherichia coli using DHO as substrate measured after ...More data for this Ligand-Target Pair