Compile Data Set for Download or QSAR
maximum 50k data
Found 3 of ic50 for monomerid = 50177054
TargetMetabotropic glutamate receptor 1(RAT)
Biocampus

Curated by ChEMBL
LigandPNGBDBM50177054(9-(1'-cyanomethylamino)-3-(4'-ethylphenyl)-3H-5-th...)
Affinity DataIC50:  43nMAssay Description:Inhibition of rat mGluR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177054(9-(1'-cyanomethylamino)-3-(4'-ethylphenyl)-3H-5-th...)
Affinity DataIC50:  49nMAssay Description:Antagonist activity at human mGluR1 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177054(9-(1'-cyanomethylamino)-3-(4'-ethylphenyl)-3H-5-th...)
Affinity DataIC50:  2.10E+3nMAssay Description:Antagonist activity at human mGluR5 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed