Compile Data Set for Download or QSAR
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Found 3 of ic50 for monomerid = 50248133
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50248133(CHEMBL518644 | N-((1s,4R)-4-cyano-4-cyclopropylcyc...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of FLAG-tagged full length human 11beta-HSD1 expressed in baculovirus-infected Trichoplusia ni Hi5 cells assessed as reduction of [3H]cort...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50248133(CHEMBL518644 | N-((1s,4R)-4-cyano-4-cyclopropylcyc...)
Affinity DataIC50:  36nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50248133(CHEMBL518644 | N-((1s,4R)-4-cyano-4-cyclopropylcyc...)
Affinity DataIC50:  64nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in presence of 3% human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed