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Found 6 of ic50 for monomerid = 50252968
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50252968(CHEMBL522363 | N-{4-[(2-Amino-6-methyl-4-oxo-3,4-d...)
Affinity DataIC50:  8nMAssay Description:Inhibition of Toxoplasma gondii DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50252968(CHEMBL522363 | N-{4-[(2-Amino-6-methyl-4-oxo-3,4-d...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50252968(CHEMBL522363 | N-{4-[(2-Amino-6-methyl-4-oxo-3,4-d...)
Affinity DataIC50:  36nMAssay Description:Inhibition of Toxoplasma gondii thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50252968(CHEMBL522363 | N-{4-[(2-Amino-6-methyl-4-oxo-3,4-d...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Escherichia coli thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50252968(CHEMBL522363 | N-{4-[(2-Amino-6-methyl-4-oxo-3,4-d...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50252968(CHEMBL522363 | N-{4-[(2-Amino-6-methyl-4-oxo-3,4-d...)
Affinity DataIC50:  200nMAssay Description:Inhibition of Escherichia coli DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed