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Found 6 of ic50 for monomerid = 50357652
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50357652(CHEMBL1914726)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of mTOR using GFP-tagged 4E-BP1 after 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50357652(CHEMBL1914726)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human VPS34 assessed as ADP formation using ATP by fluorescence-based immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357652(CHEMBL1914726)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kdelta expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357652(CHEMBL1914726)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kgamma expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357652(CHEMBL1914726)
Affinity DataIC50:  10nMAssay Description:Inhibition of N-terminus polyHis-tagged human recombinant PI3Kbeta expressed in baculovirus infected insect Sf9 cells using phosphoinositol-4,5-bisph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50357652(CHEMBL1914726)
Affinity DataIC50:  12nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser 473 in human U87MG cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed