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Found 3 of ic50 for monomerid = 50358199
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50358199(CHEMBL1921983)
Affinity DataIC50:  100nMAssay Description:Inhibition of 17,20-lyase activity of Sprague-Dawley rat testicular microsomal CYP17A1 using [1,2-3H]-17a-hydroxyprogesterone as substrate after 15 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50358199(CHEMBL1921983)
Affinity DataIC50:  290nMAssay Description:Inhibition of 17,20-lyase activity of human CYP17A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50358199(CHEMBL1921983)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human CYP3A4 assessed as conversion of testosterone into 6-hydroxytestosterone after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed