Compile Data Set for Download or QSAR
maximum 50k data
Found 36 of ic50 for monomerid = 50383191
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  1nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  1nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  1nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  10nMAssay Description:Inhibition of IGF1R by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  10nMAssay Description:Inhibition of VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  10nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  10nMAssay Description:Inhibition of RETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  10nMAssay Description:Inhibition of VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  10nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  10nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  10nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  10nMAssay Description:Inhibition of BTKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  10nMAssay Description:Inhibition of IRKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  10nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  20nMAssay Description:Inhibition of HGF-mediated c-Met autophosphorylation in human PC3 cells after 10 mins by quantitative electrochemiluminescent immunoassayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  20nMAssay Description:Inhibition of HGF-mediated c-met autophosphorylation in serum-starved human PC3 cells after 1 hr by electrochemiluminescent immunoassayMore data for this Ligand-Target Pair
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  100nMAssay Description:Inhibition of TIE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  100nMAssay Description:Inhibition of c-KITMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of aurora-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of FGFRKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of PKBalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of JAK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of aurora-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of MSK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of PIM2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of PKBbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of ERK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of PIM1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of PKAalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383191(CHEMBL2031893)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed