Compile Data Set for Download or QSAR
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Found 3 of ic50 for monomerid = 50416875
TargetCytochrome P450 2D6(Homo sapiens (Human))
Leo Pharma

US Patent
LigandPNGBDBM50416875(AMG-073 | AMG073 HCL | CINACALCET | CINACALCET HYD...)
Affinity DataIC50:  50nMpH: 7.4 T: 2°CAssay Description:Incubations were conducted in 96 well microtiter plates based on a method described by BD Biosciences. To the first well in each row, a NADPH regener...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2D6(Homo sapiens (Human))
Leo Pharma

US Patent
LigandPNGBDBM50416875(AMG-073 | AMG073 HCL | CINACALCET | CINACALCET HYD...)
Affinity DataIC50: <100nMAssay Description:Inhibition of recombinant human CYP2D6 expressed in bacterial membranes using AMMC as substrate preincubated for 10 mins followed by NADPH addition m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme 2(Homo sapiens (Human))
University Of California San Francisco (Ucsf)

Curated by ChEMBL
LigandPNGBDBM50416875(AMG-073 | AMG073 HCL | CINACALCET | CINACALCET HYD...)
Affinity DataIC50:  2.82E+4nMAssay Description:Inhibition of recombinant human ACE2 using MCA-Tyr-Val-Ala-Asp-Ala-Pro-Lys(DNP)-OH as substrate preincubated for 15 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed