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Found 2 of ic50 for monomerid = 50433562
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50433562(CHEMBL1818538 | Nutlin-1)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at human GST-tagged MDM2 assessed as inhibition of binding to full length p53More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50433562(CHEMBL1818538 | Nutlin-1)
Affinity DataIC50:  260nMAssay Description:Inhibition of recombinant p53 protein binding to recombinant human MDM2 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed