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Found 10 of ic50 for monomerid = 50507688
TargetHistone deacetylase 6(Homo sapiens (Human))
Annji Pharmaceutical

US Patent
LigandPNGBDBM50507688(CHEMBL4550214 | US11535598, Compound 5)
Affinity DataIC50:  4nMAssay Description:The IC50 values for aforementioned compounds against HDACs were determined. HDAC 1 to 11 can be assayed by using acetylated AMC-labeled peptide subst...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Annji Pharmaceutical

US Patent
LigandPNGBDBM50507688(CHEMBL4550214 | US11535598, Compound 5)
Affinity DataIC50:  4nMAssay Description:Inhibition of human full-length recombinant HDAC6 expressed in baculovirus infected Sf9 insect cells using fluorogenic peptide RHKKAc as substrate af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Annji Pharmaceutical

US Patent
LigandPNGBDBM50507688(CHEMBL4550214 | US11535598, Compound 5)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaternal embryonic leucine zipper kinase(Homo sapiens (Human))
Cedilla Therapeutics

Curated by ChEMBL
LigandPNGBDBM50507688(CHEMBL4550214 | US11535598, Compound 5)
Affinity DataIC50:  200nMAssay Description:Inhibition of MELK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Annji Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50507688(CHEMBL4550214 | US11535598, Compound 5)
Affinity DataIC50:  309nMAssay Description:Inhibition of human full-length recombinant HDAC8 expressed in baculovirus infected Sf9 insect cells using fluorogenic peptide RHKAcKAc as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Annji Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50507688(CHEMBL4550214 | US11535598, Compound 5)
Affinity DataIC50:  376nMAssay Description:The IC50 values for aforementioned compounds against HDACs were determined. HDAC 1 to 11 can be assayed by using acetylated AMC-labeled peptide subst...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Annji Pharmaceutical

US Patent
LigandPNGBDBM50507688(CHEMBL4550214 | US11535598, Compound 5)
Affinity DataIC50:  1.12E+4nMAssay Description:The IC50 values for aforementioned compounds against HDACs were determined. HDAC 1 to 11 can be assayed by using acetylated AMC-labeled peptide subst...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Annji Pharmaceutical

US Patent
LigandPNGBDBM50507688(CHEMBL4550214 | US11535598, Compound 5)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of human full-length recombinant HDAC1 expressed in baculovirus infected Sf9 insect cells using fluorogenic peptide RHKKAc as substrate af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Annji Pharmaceutical

US Patent
LigandPNGBDBM50507688(CHEMBL4550214 | US11535598, Compound 5)
Affinity DataIC50:  1.39E+4nMAssay Description:The IC50 values for aforementioned compounds against HDACs were determined. HDAC 1 to 11 can be assayed by using acetylated AMC-labeled peptide subst...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 11(Homo sapiens (Human))
Annji Pharmaceutical

US Patent
LigandPNGBDBM50507688(CHEMBL4550214 | US11535598, Compound 5)
Affinity DataIC50:  1.39E+4nMAssay Description:Inhibition of human full-length recombinant HDAC11 expressed in baculovirus infected Sf9 insect cells using fluorogenic peptide RHKKAc as substrate a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed