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Found 2 of ki for monomerid = 127403
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM127403(US8791131, 168)
Affinity DataKi:  0.204nM ΔG°:  -55.3kJ/molepH: 7.5 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against mTOR using an in vitro kinase assay. mTOR activity is measured in vitro by dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM127403(US8791131, 168)
Affinity DataKi:  4.17nM ΔG°:  -47.8kJ/molepH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kalpha using an in vitro kinase assay. PI3-Kalpha activity is measured in v...More data for this Ligand-Target Pair
In DepthDetails US Patent