Affinity DataKi: 0.140nMAssay Description:Displacement of [3H]DAMGO from mu-opioid receptor expressed in CHOK1 cells after overnight incubation by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair
Affinity DataKi: 0.320nM ΔG°: -54.2kJ/molepH: 7.5 T: 2°CAssay Description:The Ki (binding affinity) for u opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal o...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan-Kettering Cancer Center
Curated by PDSP Ki Database
Memorial Sloan-Kettering Cancer Center
Curated by PDSP Ki Database
Affinity DataKi: 0.5nMAssay Description:Binding affinity of the compound towards opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 0.530nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of Hungarian Academy of Sciences
Curated by PDSP Ki Database
Biological Research Center of Hungarian Academy of Sciences
Curated by PDSP Ki Database
Affinity DataKi: 0.780nMAssay Description:mu-1 receptor binding affinity in rat brain by 3H [d-Ala2, d-Leu5] enkephalin displacement.More data for this Ligand-Target Pair
Affinity DataKi: 0.880nMAssay Description:Binding affinity to displace radioligand [3H]DAMGO on Opioid receptor mu 1 in guinea pig membranes.More data for this Ligand-Target Pair
Affinity DataKi: 0.880nMAssay Description:Binding affinity towards Opioid receptor mu 1 of guinea pig brain membranes using radioligand 0.25 nM [3H]DAMGOMore data for this Ligand-Target Pair
Affinity DataKi: 0.880nMAssay Description:Inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 of Chinese hamster ovary membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.880nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.880nMAssay Description:Displacement of [3H]DAMGO form mu opioid receptor in guinea pig brainMore data for this Ligand-Target Pair
Affinity DataKi: 0.880nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding affinity of compound evaluated for Opioid receptor mu 1 isolated from rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]DAMGO from human cloned mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in guinea pig forebrain homogenate by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]DAMGO from human recombinant MOR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan-Kettering Cancer Center
Curated by PDSP Ki Database
Memorial Sloan-Kettering Cancer Center
Curated by PDSP Ki Database
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in CD1 mouse whole brain minus cerebellum membranes by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan-Kettering Cancer Center
Curated by PDSP Ki Database
Memorial Sloan-Kettering Cancer Center
Curated by PDSP Ki Database
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in CD1 mouse brain membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of Hungarian Academy of Sciences
Curated by PDSP Ki Database
Biological Research Center of Hungarian Academy of Sciences
Curated by PDSP Ki Database
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan-Kettering Cancer Center
Curated by PDSP Ki Database
Memorial Sloan-Kettering Cancer Center
Curated by PDSP Ki Database
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster
Curated by ChEMBL
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Binding affinity for the Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Binding affinity towards mu opioid receptor was determinedMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan-Kettering Cancer Center
Curated by PDSP Ki Database
Memorial Sloan-Kettering Cancer Center
Curated by PDSP Ki Database
Affinity DataKi: 1.80nMAssay Description:Binding affinity against mu opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Inhibition of binding of [3H]DAMGO to opioid receptor mu 1 from rat brain membrane.More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Binding affinity of the compound was determined by inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 from rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [125I]-IBOxyA from MOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.98nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in guinea pig forebrain homogenatesMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster
Curated by ChEMBL
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]-DPDPE from delta opioid receptor in rat brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster
Curated by ChEMBL
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Compound was evaluated for binding affinity towards mu-specific opiate receptor from combinatorial peptoid libraryMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Ability to displace [3H]-naloxone from the Opioid receptor mu 1 isolated from the rat brain membranes.More data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Inhibition of [3H]DAGO binding to mu 1 opioid receptor in rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK-293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair