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Found 3 Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50087016'
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087016(8-Acenaphthen-1-yl-1-phenyl-1,3,8-triaza-spiro[4.5...)
Affinity DataKi:  5.90nMAssay Description:Competitive binding displacement analyses was performed from permanently transfected HEK293 cells expressing human Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087016(8-Acenaphthen-1-yl-1-phenyl-1,3,8-triaza-spiro[4.5...)
Affinity DataKi:  12.9nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087016(8-Acenaphthen-1-yl-1-phenyl-1,3,8-triaza-spiro[4.5...)
Affinity DataEC50:  2.50E+3nMAssay Description:Effective concentration of the required to stimulate binding of GTPgammaS to mu1 receptor was determined using scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed