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Found 5 of ic50 for monomerid = 110190
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Guru Ghasidas Vishwavidyalaya (A Central University)

Curated by ChEMBL
LigandPNGBDBM110190(1-(2,4-Dihydroxyphenyl)-3-(furan-2-yl)propenone (1...)
Affinity DataIC50:  2.49E+3nMAssay Description:Competitive inhibition of PTP1B (unknown origin) using p-nitrophenyl phosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Ewha Womans University

LigandPNGBDBM110190(1-(2,4-Dihydroxyphenyl)-3-(furan-2-yl)propenone (1...)
Affinity DataIC50:  2.54E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of m-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 100 mM NaCl, 5 mM β-mercaptoethanol, and 1 mM EDTA, pH 7.5) with 50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Ewha Womans University

LigandPNGBDBM110190(1-(2,4-Dihydroxyphenyl)-3-(furan-2-yl)propenone (1...)
Affinity DataIC50:  6.06E+4nMpH: 5.5 T: 2°CAssay Description:Inhibition of cathepsin B was assayed in reaction buffer (50 mM NaOAc-HCl, 2 mM dithiothreitol, 2 mM EDTA, pH 5.5) containing 20 µM substrate an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Ewha Womans University

LigandPNGBDBM110190(1-(2,4-Dihydroxyphenyl)-3-(furan-2-yl)propenone (1...)
Affinity DataIC50:  8.67E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of µ-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 50 mM NaCl, 1 mM EDTA, 1 mM EGTA and 5 mM β-mercaptoethanol, pH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Ewha Womans University

LigandPNGBDBM110190(1-(2,4-Dihydroxyphenyl)-3-(furan-2-yl)propenone (1...)
Affinity DataIC50:  9.05E+4nMpH: 5.5 T: 2°CAssay Description:Inhibition of cathepsin L was assayed in reaction buffer (0.1M NaOAc-HCl, 1 mM EDTA, 0.1% β-mercaptoethanol, pH 5.5) containing 20 µM subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed