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TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM620450((S)-5-((1-(difluoromethyl)-5-methyl-1H-pyrazol-4-y...)
Affinity DataIC50:  1.80nMAssay Description:A fluorescent probe containing an Oregon green fluorophore was synthesized from a compound known to bind to RIPK1.The assay was performed in a buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM620443(US11767310, Example 11)
Affinity DataIC50:  2nMAssay Description:A fluorescent probe containing an Oregon green fluorophore was synthesized from a compound known to bind to RIPK1.The assay was performed in a buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM620438(US11767310, Example 6)
Affinity DataIC50:  3nMAssay Description:A fluorescent probe containing an Oregon green fluorophore was synthesized from a compound known to bind to RIPK1.The assay was performed in a buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM620434(US11767310, Example 2)
Affinity DataIC50:  4nMAssay Description:A fluorescent probe containing an Oregon green fluorophore was synthesized from a compound known to bind to RIPK1.The assay was performed in a buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM620440(US11767310, Example 8)
Affinity DataIC50:  6nMAssay Description:A fluorescent probe containing an Oregon green fluorophore was synthesized from a compound known to bind to RIPK1.The assay was performed in a buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM620439(US11767310, Example 7)
Affinity DataIC50:  7nMAssay Description:A fluorescent probe containing an Oregon green fluorophore was synthesized from a compound known to bind to RIPK1.The assay was performed in a buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM620446(US11767310, Example 14)
Affinity DataIC50:  8nMAssay Description:A fluorescent probe containing an Oregon green fluorophore was synthesized from a compound known to bind to RIPK1.The assay was performed in a buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM620433(US11767310, Example 1)
Affinity DataIC50:  11nMAssay Description:A fluorescent probe containing an Oregon green fluorophore was synthesized from a compound known to bind to RIPK1.The assay was performed in a buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM620444(US11767310, Example 12)
Affinity DataIC50:  13nMAssay Description:A fluorescent probe containing an Oregon green fluorophore was synthesized from a compound known to bind to RIPK1.The assay was performed in a buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM620437(US11767310, Example 5)
Affinity DataIC50:  14nMAssay Description:A fluorescent probe containing an Oregon green fluorophore was synthesized from a compound known to bind to RIPK1.The assay was performed in a buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM620441(US11767310, Example 9)
Affinity DataIC50:  18nMAssay Description:A fluorescent probe containing an Oregon green fluorophore was synthesized from a compound known to bind to RIPK1.The assay was performed in a buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM620436(US11767310, Example 4)
Affinity DataIC50:  30nMAssay Description:A fluorescent probe containing an Oregon green fluorophore was synthesized from a compound known to bind to RIPK1.The assay was performed in a buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM620449(US11767310, Example 17)
Affinity DataIC50:  32nMAssay Description:A fluorescent probe containing an Oregon green fluorophore was synthesized from a compound known to bind to RIPK1.The assay was performed in a buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM620435(US11767310, Example 3)
Affinity DataIC50:  36nMAssay Description:A fluorescent probe containing an Oregon green fluorophore was synthesized from a compound known to bind to RIPK1.The assay was performed in a buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM620442(US11767310, Example 10)
Affinity DataIC50:  43nMAssay Description:A fluorescent probe containing an Oregon green fluorophore was synthesized from a compound known to bind to RIPK1.The assay was performed in a buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM620445(US11767310, Example 13)
Affinity DataIC50:  95nMAssay Description:A fluorescent probe containing an Oregon green fluorophore was synthesized from a compound known to bind to RIPK1.The assay was performed in a buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM620448(US11767310, Example 16)
Affinity DataIC50:  515nMAssay Description:A fluorescent probe containing an Oregon green fluorophore was synthesized from a compound known to bind to RIPK1.The assay was performed in a buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine deaminase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50401837(CHEMBL2203870)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of guanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent RNA helicase SUPV3L1, mitochondrial(Homo sapiens)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50474366(CHEMBL2112136)
Affinity DataIC50:  6.47E+3nMAssay Description:Inhibitory activity determined against human Suv3 helicase using DNA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM620447(US11767310, Example 15)
Affinity DataIC50:  2.50E+4nMAssay Description:A fluorescent probe containing an Oregon green fluorophore was synthesized from a compound known to bind to RIPK1.The assay was performed in a buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-dependent RNA helicase SUPV3L1, mitochondrial(Homo sapiens)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50474374(CHEMBL501187)
Affinity DataIC50:  5.32E+4nMAssay Description:Inhibitory activity against human Suv3 helicase using RNA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent RNA helicase SUPV3L1, mitochondrial(Homo sapiens)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50474372(CHEMBL3114565)
Affinity DataIC50:  5.60E+4nMAssay Description:Inhibitory activity against human Suv3 helicase using RNA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent RNA helicase SUPV3L1, mitochondrial(Homo sapiens)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50474368(CHEMBL3114564)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibitory activity against human Suv3 helicase using RNA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent RNA helicase SUPV3L1, mitochondrial(Homo sapiens)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50474370(CHEMBL3114563)
Affinity DataIC50:  3.12E+5nMAssay Description:Inhibitory activity against human Suv3 helicase using RNA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent RNA helicase SUPV3L1, mitochondrial(Homo sapiens)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50474371(CHEMBL2111998)
Affinity DataIC50:  3.23E+5nMAssay Description:Inhibitory activity against human Suv3 helicase using RNA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent RNA helicase SUPV3L1, mitochondrial(Homo sapiens)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50474371(CHEMBL2111998)
Affinity DataIC50:  5.39E+5nMAssay Description:Inhibitory activity determined against human Suv3 helicase using DNA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent RNA helicase SUPV3L1, mitochondrial(Homo sapiens)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50474368(CHEMBL3114564)
Affinity DataIC50:  5.90E+5nMAssay Description:Inhibitory activity determined against human Suv3 helicase using DNA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent RNA helicase SUPV3L1, mitochondrial(Homo sapiens)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50474374(CHEMBL501187)
Affinity DataIC50: >8.86E+5nMAssay Description:Inhibitory activity determined against human Suv3 helicase using DNA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent RNA helicase SUPV3L1, mitochondrial(Homo sapiens)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50474372(CHEMBL3114565)
Affinity DataIC50: >9.33E+5nMAssay Description:Inhibitory activity determined against human Suv3 helicase using DNA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent RNA helicase SUPV3L1, mitochondrial(Homo sapiens)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50474370(CHEMBL3114563)
Affinity DataIC50: >1.04E+6nMAssay Description:Inhibitory activity determined against human Suv3 helicase using DNA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent RNA helicase SUPV3L1, mitochondrial(Homo sapiens)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50474365(CHEMBL145949)
Affinity DataIC50: >1.06E+6nMAssay Description:Inhibitory activity against human Suv3 helicase using RNA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent RNA helicase SUPV3L1, mitochondrial(Homo sapiens)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50474365(CHEMBL145949)
Affinity DataIC50: >1.06E+6nMAssay Description:Inhibitory activity determined against human Suv3 helicase using DNA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent RNA helicase SUPV3L1, mitochondrial(Homo sapiens)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50474366(CHEMBL2112136)
Affinity DataIC50: >1.07E+6nMAssay Description:Inhibitory activity against human Suv3 helicase using RNA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent RNA helicase SUPV3L1, mitochondrial(Homo sapiens)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50474369(CHEMBL3114562)
Affinity DataIC50: >1.10E+6nMAssay Description:Inhibitory activity determined against human Suv3 helicase using DNA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent RNA helicase SUPV3L1, mitochondrial(Homo sapiens)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50474369(CHEMBL3114562)
Affinity DataIC50:  1.10E+6nMAssay Description:Inhibitory activity against human Suv3 helicase using RNA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent RNA helicase SUPV3L1, mitochondrial(Homo sapiens)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50474373(CHEMBL611608)
Affinity DataIC50: >1.29E+6nMAssay Description:Inhibitory activity against human Suv3 helicase using RNA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent RNA helicase SUPV3L1, mitochondrial(Homo sapiens)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50474373(CHEMBL611608)
Affinity DataIC50: >1.29E+6nMAssay Description:Inhibitory activity determined against human Suv3 helicase using DNA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent RNA helicase SUPV3L1, mitochondrial(Homo sapiens)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50474367(CHEMBL344336)
Affinity DataIC50: >1.43E+6nMAssay Description:Inhibitory activity determined against human Suv3 helicase using DNA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent RNA helicase SUPV3L1, mitochondrial(Homo sapiens)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50474367(CHEMBL344336)
Affinity DataIC50: >1.43E+6nMAssay Description:Inhibitory activity against human Suv3 helicase using RNA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed