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Found 24 Enz. Inhib. hit(s) with all data for entry = 5757
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM93118(PTP1B Inhibitor, 19)
Affinity DataKi:  2.50E+4nM IC50:  6.27E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM93109(PTP1B Inhibitor, 5)
Affinity DataKi:  3.00E+4nM IC50:  7.00E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM93111(PTP1B Inhibitor, 7)
Affinity DataKi:  3.40E+4nM IC50:  8.70E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM93113(PTP1B Inhibitor, 11)
Affinity DataKi:  4.80E+4nM IC50:  6.70E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM93112(PTP1B Inhibitor, 10)
Affinity DataKi:  4.80E+4nM IC50:  6.90E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50487364(CHEMBL2259741)
Affinity DataKi:  4.80E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50487368(CHEMBL2259740)
Affinity DataKi:  4.80E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM93110(PTP1B Inhibitor, 6)
Affinity DataKi:  5.60E+4nM IC50:  9.10E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM93116(PTP1B Inhibitor, 14)
Affinity DataKi:  6.30E+4nM IC50:  8.80E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50487366(CHEMBL2259730)
Affinity DataKi:  6.30E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM93117(PTP1B Inhibitor, 15)
Affinity DataKi:  1.35E+5nM IC50:  1.65E+5nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50487365(CHEMBL2259731)
Affinity DataKi:  1.35E+5nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM93115(PTP1B Inhibitor, 13)
Affinity DataKi:  1.50E+5nM IC50:  2.75E+5nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50487367(CHEMBL2259743)
Affinity DataKi:  1.50E+5nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM93114(PTP1B Inhibitor, 12)
Affinity DataKi:  1.70E+5nM IC50:  4.85E+5nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50487369(CHEMBL2259742)
Affinity DataKi:  1.70E+5nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50487364(CHEMBL2259741)
Affinity DataIC50:  6.70E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50487368(CHEMBL2259740)
Affinity DataIC50:  6.90E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50182135(3-(4-methoxybenzofuran-5-yl)-5-phenyl-4,5-dihydroi...)
Affinity DataIC50:  7.60E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50182133(3-(4-methoxybenzofuran-5-yl)-5-(4-methoxyphenyl)-4...)
Affinity DataIC50:  8.10E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50487366(CHEMBL2259730)
Affinity DataIC50:  8.80E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50487365(CHEMBL2259731)
Affinity DataIC50:  1.65E+5nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50487367(CHEMBL2259743)
Affinity DataIC50:  2.75E+5nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

LigandPNGBDBM50487369(CHEMBL2259742)
Affinity DataIC50:  4.85E+5nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article