Compile Data Set for Download or QSAR
maximum 50k data
Found 72 Enz. Inhib. hit(s) with all data for entry = 50018190
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192518(1-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)...)
Affinity DataKi:  2nMAssay Description:Inhibition of [125I]MCH binding to rat MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50192518(1-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of [125I]MCH binding to mouse MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192518(1-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)...)
Affinity DataKi:  4.70nMAssay Description:Inhibition of [125I]MCH binding to human MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192518(1-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)...)
Affinity DataKi:  13nMAssay Description:Activity at human MCHR1 expressed in CHOK1-Gqi cells assessed as inhibition of MCH-induced calcium ion release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192518(1-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)...)
Affinity DataKi:  13nMAssay Description:Activity at rat MCHR1 expressed in CHOK1-Gqi cells assessed as inhibition of MCH-induced calcium ion release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50192518(1-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)...)
Affinity DataKi:  14nMAssay Description:Activity at mouse MCHR1 expressed in CHOK1-Gqi cells assessed as inhibition of MCH-induced calcium ion release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192528(1-(2-(4-fluoro-3-methylphenoxy)-5-((2-(pyrrolidin-...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of [125I]MCH binding to human MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192536(1-(2-(3,4-difluorophenoxy)-5-((2-(pyrrolidin-1-yl)...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of [125I]MCH binding to human MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192521(1-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)...)
Affinity DataIC50:  2nMAssay Description:Inhibition of [125I]MCH binding to human MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192534(1-(5-((2-(pyrrolidin-1-yl)ethyl)carbamoyl)-2-(p-to...)
Affinity DataIC50:  2nMAssay Description:Inhibition of [125I]MCH binding to human MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192535(1-(5-((2-(pyrrolidin-1-yl)ethyl)carbamoyl)-2-(m-to...)
Affinity DataIC50:  2nMAssay Description:Inhibition of [125I]MCH binding to human MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192518(1-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)...)
Affinity DataIC50:  3nMAssay Description:Inhibition of [125I]MCH binding to rat MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192521(1-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)...)
Affinity DataIC50:  3nMAssay Description:Inhibition of [125I]MCH binding to rat MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192522(1-(4-bromophenyl)-3-(2-(3,4-dimethylphenoxy)-5-((2...)
Affinity DataIC50:  5nMAssay Description:Inhibition of [125I]MCH binding to rat MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50192518(1-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)...)
Affinity DataIC50:  5nMAssay Description:Inhibition of [125I]MCH binding to mouse MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192528(1-(2-(4-fluoro-3-methylphenoxy)-5-((2-(pyrrolidin-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of [125I]MCH binding to rat MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192535(1-(5-((2-(pyrrolidin-1-yl)ethyl)carbamoyl)-2-(m-to...)
Affinity DataIC50:  7nMAssay Description:Inhibition of [125I]MCH binding to rat MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192518(1-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)...)
Affinity DataIC50:  7nMAssay Description:Inhibition of [125I]MCH binding to human MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50192531(1-(2-chlorophenyl)-3-(2-(3,4-dimethylphenoxy)-5-((...)
Affinity DataIC50:  7nMAssay Description:Inhibition of [125I]MCH binding to mouse MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192516(1-(2-(3-fluorophenoxy)-5-((2-(pyrrolidin-1-yl)ethy...)
Affinity DataIC50:  9nMAssay Description:Inhibition of [125I]MCH binding to human MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192522(1-(4-bromophenyl)-3-(2-(3,4-dimethylphenoxy)-5-((2...)
Affinity DataIC50:  11nMAssay Description:Inhibition of [125I]MCH binding to human MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192531(1-(2-chlorophenyl)-3-(2-(3,4-dimethylphenoxy)-5-((...)
Affinity DataIC50:  14nMAssay Description:Inhibition of [125I]MCH binding to rat MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192531(1-(2-chlorophenyl)-3-(2-(3,4-dimethylphenoxy)-5-((...)
Affinity DataIC50:  15nMAssay Description:Inhibition of [125I]MCH binding to human MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192536(1-(2-(3,4-difluorophenoxy)-5-((2-(pyrrolidin-1-yl)...)
Affinity DataIC50:  28nMAssay Description:Inhibition of [125I]MCH binding to rat MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50192522(1-(4-bromophenyl)-3-(2-(3,4-dimethylphenoxy)-5-((2...)
Affinity DataIC50:  28nMAssay Description:Inhibition of [125I]MCH binding to mouse MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192534(1-(5-((2-(pyrrolidin-1-yl)ethyl)carbamoyl)-2-(p-to...)
Affinity DataIC50:  33nMAssay Description:Inhibition of [125I]MCH binding to rat MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192516(1-(2-(3-fluorophenoxy)-5-((2-(pyrrolidin-1-yl)ethy...)
Affinity DataIC50:  40nMAssay Description:Inhibition of [125I]MCH binding to rat MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192526(3-(3-biphenyl-4-yl-ureido)-4-(3,4-dimethyl-phenoxy...)
Affinity DataIC50:  140nMAssay Description:Inhibition of [125I]MCH binding to human MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192530(4-(3,4-dimethylphenoxy)-3-((1R,2R)-2-phenylcyclopr...)
Affinity DataIC50:  170nMAssay Description:Inhibition of [125I]MCH binding to human MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192527(3-cinnamamido-4-(3,4-dimethylphenoxy)-N-(2-(pyrrol...)
Affinity DataIC50:  170nMAssay Description:Inhibition of [125I]MCH binding to rat MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50192527(3-cinnamamido-4-(3,4-dimethylphenoxy)-N-(2-(pyrrol...)
Affinity DataIC50:  230nMAssay Description:Inhibition of [125I]MCH binding to mouse MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192532(4-(3,4-dimethylphenoxy)-3-(3-phenylpropanamido)-N-...)
Affinity DataIC50:  250nMAssay Description:Inhibition of [125I]MCH binding to rat MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192526(3-(3-biphenyl-4-yl-ureido)-4-(3,4-dimethyl-phenoxy...)
Affinity DataIC50:  260nMAssay Description:Inhibition of [125I]MCH binding to rat MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192530(4-(3,4-dimethylphenoxy)-3-((1R,2R)-2-phenylcyclopr...)
Affinity DataIC50:  320nMAssay Description:Inhibition of [125I]MCH binding to rat MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192532(4-(3,4-dimethylphenoxy)-3-(3-phenylpropanamido)-N-...)
Affinity DataIC50:  330nMAssay Description:Inhibition of [125I]MCH binding to human MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192533(1-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)...)
Affinity DataIC50:  340nMAssay Description:Inhibition of [125I]MCH binding to human MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50192520(4-(naphthalen-2-yloxy)-3-(3-phenylpropanamido)-N-(...)
Affinity DataIC50:  340nMAssay Description:Inhibition of [125I]MCH binding to mouse MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192520(4-(naphthalen-2-yloxy)-3-(3-phenylpropanamido)-N-(...)
Affinity DataIC50:  380nMAssay Description:Inhibition of [125I]MCH binding to human MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50192526(3-(3-biphenyl-4-yl-ureido)-4-(3,4-dimethyl-phenoxy...)
Affinity DataIC50:  400nMAssay Description:Inhibition of [125I]MCH binding to mouse MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50192533(1-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)...)
Affinity DataIC50:  460nMAssay Description:Inhibition of [125I]MCH binding to mouse MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192520(4-(naphthalen-2-yloxy)-3-(3-phenylpropanamido)-N-(...)
Affinity DataIC50:  540nMAssay Description:Inhibition of [125I]MCH binding to rat MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192527(3-cinnamamido-4-(3,4-dimethylphenoxy)-N-(2-(pyrrol...)
Affinity DataIC50:  540nMAssay Description:Inhibition of [125I]MCH binding to human MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50192532(4-(3,4-dimethylphenoxy)-3-(3-phenylpropanamido)-N-...)
Affinity DataIC50:  610nMAssay Description:Inhibition of [125I]MCH binding to mouse MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192533(1-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)...)
Affinity DataIC50:  610nMAssay Description:Inhibition of [125I]MCH binding to rat MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50192519(4-(3,4-dimethylphenylthio)-3-(3-phenylpropanamido)...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [125I]MCH binding to mouse MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50192523(CHEMBL385215 | N-(2-aminoethyl)-4-(3,4-dimethylphe...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [125I]MCH binding to mouse MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50192515(CHEMBL384247 | phenyl 2-(3,4-dimethylphenoxy)-5-((...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [125I]MCH binding to mouse MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192525(3-acetamido-4-(3,4-dimethylphenoxy)-N-(2-(pyrrolid...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [125I]MCH binding to human MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192524(4-(3,4-dimethylphenoxy)-3-(2-phenylacetamido)-N-(2...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [125I]MCH binding to human MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50192514(4-(3,4-dimethylphenylamino)-3-(3-phenylpropanamido...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [125I]MCH binding to human MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 72 total ) | Next | Last >>
Jump to: