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Found 43 Enz. Inhib. hit(s) with all data for entry = 50019231
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203095(4-((4-bromo-5-methoxy-1-methyl-1H-indol-3-yl)methy...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203075(4-((4-bromo-1-methyl-1H-indol-3-yl)methylene)-3-(1...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203079(4-((4,7-dimethoxy-1-methyl-1H-indol-3-yl)methylene...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203103(4-((4-bromo-1,6-dimethyl-1H-indol-3-yl)methylene)-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203106(4-((4-methoxy-1-methyl-1H-indol-3-yl)methylene)-3-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203097(4-((4-fluoro-1-methyl-1H-indol-3-yl)methylene)-3-(...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203085(4-((4-chloro-1-methyl-1H-indol-3-yl)methylene)-3-(...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203074(4-((4-ethoxy-1-methyl-1H-indol-3-yl)methylene)-3-(...)
Affinity DataIC50:  16nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203074(4-((4-ethoxy-1-methyl-1H-indol-3-yl)methylene)-3-(...)
Affinity DataIC50:  19nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203091(4-((4-methoxy-1-methyl-1H-indol-3-yl)methylene)-3-...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203098(4-((4,7-dimethoxy-1-methyl-1H-indol-3-yl)methylene...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203089(CHEMBL398459 | methyl 1-methyl-3-((5-oxo-3-(1,2,3-...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203109(4-((4-bromo-5-methoxy-1-methyl-1H-indol-3-yl)methy...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203108(4-((4-ethoxy-1-methyl-1H-indol-3-yl)methylene)-3-(...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203078(4-((5-methoxy-1-methyl-1H-indol-3-yl)methylene)-3-...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203093(4-((5-chloro-1-methyl-1H-indol-3-yl)methylene)-3-(...)
Affinity DataIC50:  34nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203090(4-((4-bromo-1-methyl-1H-indol-3-yl)methylene)-3-(4...)
Affinity DataIC50:  34nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203077(4-((1,5-dimethyl-1H-indol-3-yl)methylene)-3-(1,2,3...)
Affinity DataIC50:  35nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203074(4-((4-ethoxy-1-methyl-1H-indol-3-yl)methylene)-3-(...)
Affinity DataIC50:  36nMAssay Description:Inhibition of TRK AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203074(4-((4-ethoxy-1-methyl-1H-indol-3-yl)methylene)-3-(...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203099(4-((4-chloro-1-methyl-1H-indol-3-yl)methylene)-3-(...)
Affinity DataIC50:  45nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203082(4-((5-fluoro-1-methyl-1H-indol-3-yl)methylene)-3-(...)
Affinity DataIC50:  48nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203081(4-((4,5,6,7-tetrahydro-1H-indol-2-yl)methylene)-3-...)
Affinity DataIC50:  56nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203107(4-((1,4-dimethyl-1H-indol-3-yl)methylene)-3-(4-met...)
Affinity DataIC50:  58nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203100(CHEMBL249381 | methyl 1-methyl-3-((5-oxo-3-(1,2,3-...)
Affinity DataIC50:  73nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203094(4-((6-chloro-1-methyl-1H-indol-3-yl)methylene)-3-(...)
Affinity DataIC50:  73nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203096(4-((4-bromo-1-methyl-1H-indol-3-yl)methylene)-3-(4...)
Affinity DataIC50:  89nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203102(4-((5-methoxy-1-methyl-1H-indol-3-yl)methylene)-3-...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203092(3-(4-methyl-1,2,3-thiadiazol-5-yl)-4-((1-methyl-1H...)
Affinity DataIC50:  95nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203083(4-((5-fluoro-1-methyl-1H-indol-3-yl)methylene)-3-(...)
Affinity DataIC50:  99nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203105(4-((7-methoxy-1-methyl-1H-indol-3-yl)methylene)-3-...)
Affinity DataIC50:  109nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203086(4-((5-bromo-1-methyl-1H-indol-3-yl)methylene)-3-(1...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203088(4-((4-fluoro-1-methyl-1H-indol-3-yl)methylene)-3-(...)
Affinity DataIC50:  137nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203084(4-((5-chloro-1-methyl-1H-indol-3-yl)methylene)-3-(...)
Affinity DataIC50:  152nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203076(1-methyl-3-((5-oxo-3-(1,2,3-thiadiazol-5-yl)-1H-py...)
Affinity DataIC50:  174nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203101(4-((3,5-dimethyl-1H-pyrrol-2-yl)methylene)-3-(4-me...)
Affinity DataIC50:  197nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203087(1-methyl-3-((3-(4-methyl-1,2,3-thiadiazol-5-yl)-5-...)
Affinity DataIC50: >300nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203080(4-((5-chloro-1H-indol-3-yl)methylene)-3-(4-methyl-...)
Affinity DataIC50: >300nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203074(4-((4-ethoxy-1-methyl-1H-indol-3-yl)methylene)-3-(...)
Affinity DataIC50:  463nMAssay Description:Inhibition of SRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203104(4-((1H-indol-3-yl)methylene)-3-(4-methyl-1,2,3-thi...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203074(4-((4-ethoxy-1-methyl-1H-indol-3-yl)methylene)-3-(...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203074(4-((4-ethoxy-1-methyl-1H-indol-3-yl)methylene)-3-(...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of cMetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50203074(4-((4-ethoxy-1-methyl-1H-indol-3-yl)methylene)-3-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed