Compile Data Set for Download or QSAR
maximum 50k data
Found 37 Enz. Inhib. hit(s) with all data for entry = 50021126
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221346(4-[2-(4-methanesulfinyl-2-methyl-phenyl)-5-(6-meth...)
Affinity DataIC50:  12nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50024795(CHEMBL2096892)
Affinity DataIC50:  22nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221354(4-(4-(6-methoxynaphthalen-2-yl)-2-(2-methyl-4-(met...)
Affinity DataIC50:  36nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221347(4-(4-(6-methoxynaphthalen-2-yl)-2-(2-methyl-4-(met...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221349(4-(2-(2-chloro-4-(methylsulfinyl)phenyl)-4-(6-meth...)
Affinity DataIC50:  51nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221352(4-(2-(2-chloro-4-(methylsulfonyl)phenyl)-4-(6-meth...)
Affinity DataIC50:  59nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50217604(4-(5-(6-methoxynaphthalen-2-yl)-1-methyl-2-(4-(met...)
Affinity DataIC50:  60nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221356(4-(2-(2,6-dichlorophenyl)-4-(6-methoxynaphthalen-2...)
Affinity DataIC50:  78nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221357(4-(2-(2-bromophenyl)-4-(6-methoxynaphthalen-2-yl)-...)
Affinity DataIC50:  82nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50024794(CHEMBL2448122)
Affinity DataIC50:  95nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221358(4-[2-(4-methanesulfonyl-2-methyl-phenyl)-5-(6-meth...)
Affinity DataIC50:  114nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221342(4-(2-(2-chlorophenyl)-4-(6-methoxynaphthalen-2-yl)...)
Affinity DataIC50:  157nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221353(4-(4-(6-methoxynaphthalen-2-yl)-2-(4-(methylsulfon...)
Affinity DataIC50:  250nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221341(4-(4-(6-methoxynaphthalen-2-yl)-2-(2-(trifluoromet...)
Affinity DataIC50:  260nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221346(4-[2-(4-methanesulfinyl-2-methyl-phenyl)-5-(6-meth...)
Affinity DataIC50:  296nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221344(4-[5-(6-methoxy-naphthalen-2-yl)-1-methyl-2-(2-met...)
Affinity DataIC50:  335nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221351(4-(2-(2-ethylphenyl)-4-(6-methoxynaphthalen-2-yl)-...)
Affinity DataIC50:  346nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221350(4-(4-(6-methoxynaphthalen-2-yl)-2-o-tolyl-1H-imida...)
Affinity DataIC50:  387nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221346(4-[2-(4-methanesulfinyl-2-methyl-phenyl)-5-(6-meth...)
Affinity DataIC50:  550nMAssay Description:Inhibition of cFMSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221345(4-(2-(2-isopropylphenyl)-4-(6-methoxynaphthalen-2-...)
Affinity DataIC50:  836nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221348(4-(4-(6-methoxynaphthalen-2-yl)-2-(2-methyl-4-(met...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221355(4-(2-(2-chloro-4-(methylthio)phenyl)-4-(6-methoxyn...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221346(4-[2-(4-methanesulfinyl-2-methyl-phenyl)-5-(6-meth...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221343(4-(2-(2-fluorophenyl)-4-(6-methoxynaphthalen-2-yl)...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221346(4-[2-(4-methanesulfinyl-2-methyl-phenyl)-5-(6-meth...)
Affinity DataIC50:  9.70E+3nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50217603(4-(4-(6-methoxynaphthalen-2-yl)-2-(4-(methylsulfin...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221346(4-[2-(4-methanesulfinyl-2-methyl-phenyl)-5-(6-meth...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of METMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221346(4-[2-(4-methanesulfinyl-2-methyl-phenyl)-5-(6-meth...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PKCbeta1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221346(4-[2-(4-methanesulfinyl-2-methyl-phenyl)-5-(6-meth...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221346(4-[2-(4-methanesulfinyl-2-methyl-phenyl)-5-(6-meth...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221346(4-[2-(4-methanesulfinyl-2-methyl-phenyl)-5-(6-meth...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221346(4-[2-(4-methanesulfinyl-2-methyl-phenyl)-5-(6-meth...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221346(4-[2-(4-methanesulfinyl-2-methyl-phenyl)-5-(6-meth...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PDGFRalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221346(4-[2-(4-methanesulfinyl-2-methyl-phenyl)-5-(6-meth...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221346(4-[2-(4-methanesulfinyl-2-methyl-phenyl)-5-(6-meth...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of KITMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221346(4-[2-(4-methanesulfinyl-2-methyl-phenyl)-5-(6-meth...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50221346(4-[2-(4-methanesulfinyl-2-methyl-phenyl)-5-(6-meth...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of INSRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed