Compile Data Set for Download or QSAR
maximum 50k data
Found 42 Enz. Inhib. hit(s) with all data for entry = 50030419
LigandPNGBDBM50295872(5-Iodo-4-(1-Methyl-1H-indol-3-yl)pyrimidin-2-amine...)
Affinity DataIC50:  400nMAssay Description:Inhibition of rat recombinant DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50295873(4-[2-Amino-4-(1H-indol-3-yl)pyrimidin-5-yl]benzami...)
Affinity DataIC50:  580nMAssay Description:Inhibition of rat recombinant DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Rattus norvegicus (rat))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295874(4-(1H-indol-3-yl)-5-(4-(trifluoromethyl)phenyl)pyr...)
Affinity DataIC50:  580nMAssay Description:Inhibition of rat recombinant Erk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50295875(4-(1H-Indol-3-yl)-5-(3-methoxyphenyl)pyrimidin-2-a...)
Affinity DataIC50:  600nMAssay Description:Inhibition of rat recombinant DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50295876(4-(1H-Indol-3-yl)-5-(3-aminophenyl)pyrimidin-2-ami...)
Affinity DataIC50:  640nMAssay Description:Inhibition of rat recombinant DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50295877(4-[2-Amino-4-(1-methyl-1H-indol-3-yl)pyrimidin-5-y...)
Affinity DataIC50:  900nMAssay Description:Inhibition of rat recombinant DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Rattus norvegicus (rat))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295878(4-(1-Methyl-1H-indol-3-yl)-5-(pyridin-4-yl)pyrimid...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of rat recombinant Erk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50295879(4-(1-Methyl-1H-indol-3-yl)-5-(3-aminophenyl)pyrimi...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of rat recombinant DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Rattus norvegicus (rat))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295873(4-[2-Amino-4-(1H-indol-3-yl)pyrimidin-5-yl]benzami...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of rat recombinant Erk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50295880(4-[2-Amino-4-(1-methyl-1H-indol-3-yl)pyrimidin-5-y...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of rat recombinant DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50295874(4-(1H-indol-3-yl)-5-(4-(trifluoromethyl)phenyl)pyr...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of rat recombinant DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50295878(4-(1-Methyl-1H-indol-3-yl)-5-(pyridin-4-yl)pyrimid...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of rat recombinant DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295872(5-Iodo-4-(1-Methyl-1H-indol-3-yl)pyrimidin-2-amine...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50295881(4-(1H-indol-3-yl)-5-(4-(trifluoromethoxy)phenyl)py...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of rat recombinant DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50295882(4-(1-Methyl-1H-indol-3-yl)-5-(3-methoxyphenyl)pyri...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of rat recombinant DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Rattus norvegicus (rat))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295875(4-(1H-Indol-3-yl)-5-(3-methoxyphenyl)pyrimidin-2-a...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of rat recombinant Erk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50295883(4-(1-Methyl-1H-indol-3-yl)-5,50-bipyrimidin-2-amin...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of rat recombinant DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Rattus norvegicus (rat))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295881(4-(1H-indol-3-yl)-5-(4-(trifluoromethoxy)phenyl)py...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of rat recombinant Erk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Rattus norvegicus (rat))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295872(5-Iodo-4-(1-Methyl-1H-indol-3-yl)pyrimidin-2-amine...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of rat recombinant Erk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50295884(1-(4-(2-amino-4-(1-methyl-1H-indol-3-yl)pyrimidin-...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of rat recombinant DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295878(4-(1-Methyl-1H-indol-3-yl)-5-(pyridin-4-yl)pyrimid...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Rattus norvegicus (rat))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295876(4-(1H-Indol-3-yl)-5-(3-aminophenyl)pyrimidin-2-ami...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of rat recombinant Erk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Rattus norvegicus (rat))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295880(4-[2-Amino-4-(1-methyl-1H-indol-3-yl)pyrimidin-5-y...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of rat recombinant Erk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295873(4-[2-Amino-4-(1H-indol-3-yl)pyrimidin-5-yl]benzami...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295881(4-(1H-indol-3-yl)-5-(4-(trifluoromethoxy)phenyl)py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295884(1-(4-(2-amino-4-(1-methyl-1H-indol-3-yl)pyrimidin-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295885(5-(biphenyl-4-yl)-4-(1-methyl-1H-indol-3-yl)pyrimi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295875(4-(1H-Indol-3-yl)-5-(3-methoxyphenyl)pyrimidin-2-a...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295882(4-(1-Methyl-1H-indol-3-yl)-5-(3-methoxyphenyl)pyri...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295876(4-(1H-Indol-3-yl)-5-(3-aminophenyl)pyrimidin-2-ami...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295879(4-(1-Methyl-1H-indol-3-yl)-5-(3-aminophenyl)pyrimi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Rattus norvegicus (rat))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295883(4-(1-Methyl-1H-indol-3-yl)-5,50-bipyrimidin-2-amin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant Erk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295880(4-[2-Amino-4-(1-methyl-1H-indol-3-yl)pyrimidin-5-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295877(4-[2-Amino-4-(1-methyl-1H-indol-3-yl)pyrimidin-5-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295883(4-(1-Methyl-1H-indol-3-yl)-5,50-bipyrimidin-2-amin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50295885(5-(biphenyl-4-yl)-4-(1-methyl-1H-indol-3-yl)pyrimi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Rattus norvegicus (rat))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295884(1-(4-(2-amino-4-(1-methyl-1H-indol-3-yl)pyrimidin-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant Erk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Rattus norvegicus (rat))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295885(5-(biphenyl-4-yl)-4-(1-methyl-1H-indol-3-yl)pyrimi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant Erk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Rattus norvegicus (rat))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295882(4-(1-Methyl-1H-indol-3-yl)-5-(3-methoxyphenyl)pyri...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant Erk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Rattus norvegicus (rat))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295879(4-(1-Methyl-1H-indol-3-yl)-5-(3-aminophenyl)pyrimi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant Erk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Rattus norvegicus (rat))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295877(4-[2-Amino-4-(1-methyl-1H-indol-3-yl)pyrimidin-5-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant Erk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295874(4-(1H-indol-3-yl)-5-(4-(trifluoromethyl)phenyl)pyr...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed