Compile Data Set for Download or QSAR
maximum 50k data
Found 41 Enz. Inhib. hit(s) with all data for entry = 50036326
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034683((S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-py...)
Affinity DataKi:  0.160nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.210nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.270nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.300nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034681(2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataKi:  0.320nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366618(CHEMBL448620 | SNAP-5089)
Affinity DataKi:  0.350nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50033111(1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetra...)
Affinity DataKi:  2.60nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50033111(1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetra...)
Affinity DataKi:  3.70nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034682((R)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-py...)
Affinity DataKi:  4.70nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50033111(1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetra...)
Affinity DataKi:  6.90nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  13nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  24nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50033111(1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetra...)
Affinity DataKi:  26nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366618(CHEMBL448620 | SNAP-5089)
Affinity DataKi:  37nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034681(2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataKi:  50nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034683((S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-py...)
Affinity DataKi:  55nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034682((R)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-py...)
Affinity DataKi:  56nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034683((S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-py...)
Affinity DataKi:  100nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034682((R)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-py...)
Affinity DataKi:  170nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50033111(1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetra...)
Affinity DataKi:  170nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  210nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034681(2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataKi:  210nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366618(CHEMBL448620 | SNAP-5089)
Affinity DataKi:  220nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034681(2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataKi:  300nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034683((S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-py...)
Affinity DataKi:  330nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366618(CHEMBL448620 | SNAP-5089)
Affinity DataKi:  370nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366618(CHEMBL448620 | SNAP-5089)
Affinity DataKi:  410nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034683((S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-py...)
Affinity DataKi:  420nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034682((R)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-py...)
Affinity DataKi:  450nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366618(CHEMBL448620 | SNAP-5089)
Affinity DataKi:  460nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034683((S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-py...)
Affinity DataKi:  530nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50033111(1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetra...)
Affinity DataKi:  550nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034681(2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataKi:  570nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034682((R)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-py...)
Affinity DataKi:  660nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366618(CHEMBL448620 | SNAP-5089)
Affinity DataKi:  780nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366618(CHEMBL448620 | SNAP-5089)
Affinity DataKi:  780nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366618(CHEMBL448620 | SNAP-5089)
Affinity DataKi:  780nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034681(2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataKi:  800nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034682((R)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-py...)
Affinity DataKi:  900nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366618(CHEMBL448620 | SNAP-5089)
Affinity DataKi:  1.10E+3nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366618(CHEMBL448620 | SNAP-5089)
Affinity DataKi:  1.20E+3nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed