Compile Data Set for Download or QSAR
maximum 50k data
Found 66 Enz. Inhib. hit(s) with all data for entry = 50002091
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM294004(5-((2S)-2-(4-((2- Trifluoromethyl-3-(2- methylphen...)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM294012((2S)-5-(2-(4-((2-Fluoro-3-(4-(2- methoxyethoxy)-2-...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM294016(1-(5-((4-((2S)-1-(1H-Tetrazol-5- yl)pent-3-yn-2- y...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM294006(5-((2S)-2-(4-((2-Cyano-3-(2- methylphenyl)benzo[b]...)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM293978((2S)-5-(2-(4-((3-(3-(2- Methoxyethoxy)-2- methylph...)
Affinity DataEC50:  54nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50453343(CHEMBL4211335)
Affinity DataEC50:  1.41E+3nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM293987(5-((2S)-2-(4-((2-Methyl-3-(2- methylphenyl)benzo[b...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM293970(5-((2S)-2-(4-((2-Chloro-3-(2- methylphenyl)benzo[b...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM294002(5-((2S)-2-(4-((2-Bromo-3-(2- methylphenyl)benzo[b]...)
Affinity DataEC50:  19nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM294003(5-((2S)-2-(4-((2-Iodo-3-(2- methylphenyl)benzo[b]t...)
Affinity DataEC50:  28nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM294031((2S)-5-(2-(4-((7-Methyl-3-(2- methylphenyl)benzo[b...)
Affinity DataEC50:  134nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM294037((2S)-5-(2-(4-((7-Fluoro-3-(2- methylphenyl)benzo[b...)
Affinity DataEC50:  23nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM294035((2S)-5-(2-(4-((7-Chloro-3-(2- methylphenyl)benzo[b...)
Affinity DataEC50:  63nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM293976((2S)-5-(2-(4-((3-(4-(2- Methoxyethoxy)-2- methylph...)
Affinity DataEC50:  9nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM293983((2S)-5-(2-(4-((3-(5-(2- Methoxyethoxy)-2- methylph...)
Affinity DataEC50:  85nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM293999(3-(4-(5-((4-((2S)-1-(1H- Tetrazol-5-yl)pent-3-yn-2...)
Affinity DataEC50:  29nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM293984((2S)-5-(2-(4-((3-(2-Methyl-4-(3- (methylsulfonyl)p...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM293980((2S)-3-((4-(5-((4-(1-(1H- Tetrazol-5-yl)pent-3-yn-...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM293981((2S)-5-(2-(4-((3-(2- (Trifluoromethyl)phenyl)benzo...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM293993((2S)-5-(5-((4-(1-(1H-Tetrazol-5- yl)pent-3-yn-2- y...)
Affinity DataEC50:  37nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM294016(1-(5-((4-((2S)-1-(1H-Tetrazol-5- yl)pent-3-yn-2- y...)
Affinity DataEC50:  83nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM294023((2S)-5-(2-(4-((3- Cyclohexylbenzo[b]thiophen-5- yl...)
Affinity DataEC50:  107nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM294014((2S)-5-(2-(4-((3-(4-(2- Methoxyethoxy)-2- methylph...)
Affinity DataEC50:  47nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM294015(5-((2S)-2-(4-((3-(4-(2- Methoxyethoxy)-2- methylph...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM293969((2S)-5-(2-(4-((3-(2- Methylphenyl)benzo[b]thiophen...)
Affinity DataEC50:  7nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM293987(5-((2S)-2-(4-((2-Methyl-3-(2- methylphenyl)benzo[b...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM293971(5-((2S)-2-(4-((2-Fluoro-3-(2- methylphenyl)benzo[b...)
Affinity DataEC50:  14nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM293970(5-((2S)-2-(4-((2-Chloro-3-(2- methylphenyl)benzo[b...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM294003(5-((2S)-2-(4-((2-Iodo-3-(2- methylphenyl)benzo[b]t...)
Affinity DataEC50:  33nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM294006(5-((2S)-2-(4-((2-Cyano-3-(2- methylphenyl)benzo[b]...)
Affinity DataEC50:  19nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM294007((2S)-5-(2-(4-((2- (Methylsulfonyl)-3-(2- methylphe...)
Affinity DataEC50:  128nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM294037((2S)-5-(2-(4-((7-Fluoro-3-(2- methylphenyl)benzo[b...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM294035((2S)-5-(2-(4-((7-Chloro-3-(2- methylphenyl)benzo[b...)
Affinity DataEC50:  108nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM294036((2S)-5-(2-(4-((7-Chloro-3-(4- methoxy-2- methylphe...)
Affinity DataEC50:  71nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM293978((2S)-5-(2-(4-((3-(3-(2- Methoxyethoxy)-2- methylph...)
Affinity DataEC50:  14nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM293983((2S)-5-(2-(4-((3-(5-(2- Methoxyethoxy)-2- methylph...)
Affinity DataEC50:  26nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM293999(3-(4-(5-((4-((2S)-1-(1H- Tetrazol-5-yl)pent-3-yn-2...)
Affinity DataEC50:  19nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM293980((2S)-3-((4-(5-((4-(1-(1H- Tetrazol-5-yl)pent-3-yn-...)
Affinity DataEC50:  6nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM293981((2S)-5-(2-(4-((3-(2- (Trifluoromethyl)phenyl)benzo...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM293979((2S)-3-(5-((4-(1-(1H-Tetrazol-5- yl)pent-3-yn-2- y...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM293990((2S)-5-(2-(4-((3-(1-Methyl-1H- pyrazol-5-yl)benzo[...)
Affinity DataEC50:  32nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM294025((2S)-5-(2-(4-((3- Cyclopropylbenzo[b]thiophen- 5-y...)
Affinity DataEC50:  239nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM294014((2S)-5-(2-(4-((3-(4-(2- Methoxyethoxy)-2- methylph...)
Affinity DataEC50:  32nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM294015(5-((2S)-2-(4-((3-(4-(2- Methoxyethoxy)-2- methylph...)
Affinity DataEC50:  14nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM293990((2S)-5-(2-(4-((3-(1-Methyl-1H- pyrazol-5-yl)benzo[...)
Affinity DataEC50:  67nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM294023((2S)-5-(2-(4-((3- Cyclohexylbenzo[b]thiophen-5- yl...)
Affinity DataEC50:  16nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM294038((2S)-5-(2-(4-((7-Fluoro-3-(4- methoxy-2- methylphe...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM294012((2S)-5-(2-(4-((2-Fluoro-3-(4-(2- methoxyethoxy)-2-...)
Affinity DataEC50:  24nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM294013((2S)-5-(2-(4-((2-Chloro-3-(4-(2- methoxyethoxy)-2-...)
Affinity DataEC50:  39nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM294004(5-((2S)-2-(4-((2- Trifluoromethyl-3-(2- methylphen...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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