Found 6 Enz. Inhib. hit(s) with all data for entry = 50004597 Target2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase(Escherichia coli (strain K12))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Inhibition of Escherichia coli HPPK using 6-hydroxymethyl-7,8-dihydropterin as substrate and [32P]-ATPMore data for this Ligand-Target Pair
Target2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase(Escherichia coli (strain K12))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of Escherichia coli HPPK using 6-hydroxymethyl-7,8-dihydropterin as substrate and [32P]-ATPMore data for this Ligand-Target Pair
3D Structure (crystal)Target2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase(Escherichia coli (strain K12))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Escherichia coli HPPK using 6-hydroxymethyl-7,8-dihydropterin as substrate and [32P]-ATPMore data for this Ligand-Target Pair
Target2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase(Escherichia coli (strain K12))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataKd: 470nMAssay Description:Binding affinity to Escherichia coli HPPK using 6-hydroxymethyl-7,8-dihydropterin as substrate and ATP by fluorometric analysisMore data for this Ligand-Target Pair
Target2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase(Escherichia coli (strain K12))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataKd: >1.50E+5nMAssay Description:Binding affinity to Escherichia coli HPPK using 6-hydroxymethyl-7,8-dihydropterin as substrate and ATP by fluorometric analysisMore data for this Ligand-Target Pair
Target2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase(Escherichia coli (strain K12))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataKd: 2.55E+3nMAssay Description:Binding affinity to Escherichia coli HPPK using 6-hydroxymethyl-7,8-dihydropterin as substrate and ATP by fluorometric analysisMore data for this Ligand-Target Pair
