Found 62 Enz. Inhib. hit(s) with all data for entry = 50009669 TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as decrease in ACh-induced channel currents at -60 mV holding potential...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as decrease in ACh-induced channel currents at -60 mV holding potential...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as decrease in ACh-induced channel currents at -60 mV holding potential...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as decrease in ACh-induced channel currents at -60 mV holding potential...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as decrease in ACh-induced channel currents at -60 mV holding potential...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as decrease in ACh-induced channel currents at -60 mV holding potential...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as decrease in ACh-induced channel currents at -60 mV holding potential...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as decrease in ACh-induced channel currents at -60 mV holding potential...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 530nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 2.50E+3nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 920nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 5.40E+3nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 120nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 890nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 1.60E+3nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 350nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in channel currents at -60 mV holding potential by tw...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 3.35E+3nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in channel currents at -60 mV holding potential by tw...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 690nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 3.35E+3nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in channel currents at -60 mV holding potential by tw...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 140nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 70nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 min...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 70nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 min...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 69nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 360nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 2.50E+3nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 920nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: >1.33E+4nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 120nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 240nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 1.60E+3nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: >1.33E+4nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 350nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in channel currents at -60 mV holding potential by tw...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 500nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 min...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 110nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 530nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 230nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 600nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in channel currents at -60 mV holding potential by tw...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 1.80E+3nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 2.10E+3nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 160nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 230nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 110nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in channel currents at -60 mV holding potential by tw...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 2.10E+3nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 70nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 min...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 360nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: >1.33E+4nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 240nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: >1.33E+4nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
