Found 36 Enz. Inhib. hit(s) with all data for entry = 50010006 
Affinity DataEC50: 20nMAssay Description:Modulation of gamma-secretase in human SK-N-BE(2) cells expressing human APP695 assessed as reduction in amyloid beta 42 production incubated overnig...More data for this Ligand-Target Pair
Affinity DataEC50: 90nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human APP695 assessed as reduction in amyloid beta 42 production after 22 hrs by electroch...More data for this Ligand-Target Pair
Affinity DataEC50: 39nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human APP751 assessed as reduction in amyloid beta 42 production after 16 to 18 hrs by san...More data for this Ligand-Target Pair
Affinity DataEC50: 5.70E+3nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human APP695 assessed as inhibition of amyloid beta 42 production after 16 hrs by sandwich...More data for this Ligand-Target Pair
Affinity DataEC50: 347nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells expressing human APP751 assessed as reduction in amyloid beta 42 production after 24 hrs by sand...More data for this Ligand-Target Pair
Affinity DataEC50: 41nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human APP751 assessed as reduction in amyloid beta 42 production after 16 to 18 hrs by san...More data for this Ligand-Target Pair
Affinity DataEC50: 4.00E+4nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing APP K595N/M596L Swedish mutant assessed as inhibition of amyloid beta 42 production measur...More data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Modulation of gamma-secretase in CHO cells expressing human APP assessed as reduction in amyloid beta (1 to 42 residues) production after 24 hrs by E...More data for this Ligand-Target Pair
Affinity DataEC50: 9nMAssay Description:Modulation of gamma-secretase in CHO cells expressing human APP assessed as reduction in amyloid beta (1 to 42 residues) production after 24 hrs by E...More data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Modulation of gamma-secretase in human SK-N-BE(2) cells expressing human APP695 assessed as reduction in amyloid beta 42 production incubated overnig...More data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Modulation of gamma-secretase in human SK-N-BE(2) cells expressing human APP695 assessed as reduction in amyloid beta 42 production incubated overnig...More data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells expressing human APP751 assessed as reduction in amyloid beta 42 production after 16 to 18 hrs b...More data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells expressing human APP751 assessed as reduction in amyloid beta 42 production after 24 hrs by sand...More data for this Ligand-Target Pair
Affinity DataEC50: 29nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells expressing human APP751 assessed as reduction in amyloid beta 42 production after 18 to 22 hrs b...More data for this Ligand-Target Pair
Affinity DataEC50: 1.50E+3nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells expressing human APP751 assessed as reduction in amyloid beta 42 production after 18 to 22 hrs b...More data for this Ligand-Target Pair
Affinity DataEC50: 29nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 42 residues) productionMore data for this Ligand-Target Pair
Affinity DataEC50: 49nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human APP751 assessed as reduction in amyloid beta 42 production after 16 to 18 hrs by san...More data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human APP751 assessed as reduction in amyloid beta 42 production after 16 to 18 hrs by san...More data for this Ligand-Target Pair
Affinity DataEC50: 105nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human APP751 assessed as reduction in amyloid beta 42 production after 16 to 18 hrs by san...More data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human APP751 assessed as reduction in amyloid beta 42 production after 16 to 18 hrs by san...More data for this Ligand-Target Pair
Affinity DataEC50: 46nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human APP695 assessed as reduction in amyloid beta 42 production after 22 hrs by electroch...More data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Modulation of human gamma-secretase assessed as inhibition of amyloid beta (1 to 42 residues) production by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 67nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human APP751 assessed as inhibition of amyloid beta 42 production after 16 to 18 hrs by EL...More data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Modulation of gamma-secretase (unknown origin) assessed as reduction in amyloid beta 42 production by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Modulation of gamma-secretase in CHO cells expressing human APP assessed as reduction in amyloid beta (1 to 42 residues) production after 24 hrs by E...More data for this Ligand-Target Pair
Affinity DataEC50: 50nMAssay Description:Modulation of gamma-secretase in human SK-N-BE(2) cells expressing human APP695 assessed as reduction in amyloid beta 42 production incubated overnig...More data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Modulation of gamma-secretase in human SK-N-BE(2) cells expressing human APP695 assessed as reduction in amyloid beta 42 production incubated overnig...More data for this Ligand-Target Pair
Affinity DataEC50: 1.30E+3nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells expressing human APP751 assessed as reduction in amyloid beta 42 production after 24 hrs by sand...More data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Modulation of gamma-secretase (unknown origin) assessed as inhibition of amyloid beta 42 productionMore data for this Ligand-Target Pair
Affinity DataEC50: 71nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human APP751 assessed as reduction in amyloid beta 42 production after 16 to 18 hrs by san...More data for this Ligand-Target Pair
Affinity DataEC50: 101nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human APP751 assessed as reduction in amyloid beta 42 production after 16 to 18 hrs by san...More data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human APP695 assessed as reduction in amyloid beta 42 production after 22 hrs by electroch...More data for this Ligand-Target Pair
Affinity DataEC50: 83nMAssay Description:Modulation of human gamma-secretase assessed as inhibition of amyloid beta (1 to 42 residues) production by ELISAMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataEC50: 25nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human APP751 assessed as reduction in amyloid beta 42 production after 16 to 18 hrs by san...More data for this Ligand-Target Pair
Affinity DataEC50: 45nMAssay Description:Modulation of gamma-secretase in human SK-N-BE(2) cells expressing human APP695 assessed as reduction in amyloid beta 42 production incubated overnig...More data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 42 residues) productionMore data for this Ligand-Target Pair
